The HDAC10 Polyclonal Antibody (AB40073) is a powerful tool for studying HDAC10, a key enzyme involved in gene regulation and cell signaling. This antibody, generated in rabbits, is highly specific for human HDAC10 and has been extensively validated for use in Western blot and immunohistochemistry applications.HDAC10, a member of the histone deacetylase family, plays a critical role in various cellular processes, including cell proliferation, differentiation, and apoptosis. Dysregulation of HDAC10 has been implicated in numerous diseases, such as cancer, neurodegenerative disorders, and inflammatory conditions.
Therefore, understanding the function and regulation of HDAC10 is essential for developing targeted therapies for these diseases.Whether investigating the role of HDAC10 in cancer progression or exploring its potential as a therapeutic target, the HDAC10 Polyclonal Antibody offers reliable and sensitive detection of HDAC10 protein levels in various cell types and tissues. This antibody is a valuable tool for researchers working in the fields of molecular biology, oncology, and drug discovery.
The protein encoded by this gene belongs to the histone deacetylase family, members of which deacetylate lysine residues on the N-terminal part of the core histones. Histone deacetylation modulates chromatin structure, and plays an important role in transcriptional regulation, cell cycle progression, and developmental events. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
83933
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from MCF7 cells, using [KD Validated] HDAC10 Rabbit pAb (CAB24335) at 1:600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
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