The HNRNPR Antibody (CAB5883) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, has high specificity and sensitivity for human samples, making it suitable for use in various applications such as Western blot and immunohistochemistry.HNRNPR is known to play a crucial role in pre-mRNA splicing and mRNA transport, making it a key player in gene expression regulation. Dysregulation of HNRNPR has been associated with various diseases, including cancer and neurodegenerative disorders, highlighting the importance of studying this protein in research settings.
This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
HNRNPR Antibody
SKU:
CAB5883
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
HNRPR, NEDDFSB, hnRNP-R, HNRNPR
Positive Sample:
U-251 MG, SK-OV-3, L-02, HL-60, Mouse brain, Rat brain
Cellular Localization:
Cytoplasm, Nucleus, Nucleoplasm.
Calculated MW:
71kDa
Observed MW:
71kDa/77kDa/80kDa
This gene encodes an RNA-binding protein that is a member of the spliceosome C complex, which functions in pre-mRNA processing and transport. The encoded protein also promotes transcription at the c-fos gene. Alternative splicing results in multiple transcript variants. There are pseudogenes for this gene on chromosomes 4, 11, and 10.
Purification Method
Affinity purification
Gene ID
10236
RRID
AB_2766631
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using HNRNPR Rabbit pAb (CAB5883) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates / proteins: 25 μg per lane. Blocking buffer: 3 % nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
