The HNRPLL Antibody (CAB10360) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity in detecting HNRPLL in human samples, making it suitable for use in Western blot applications.HNRPLL, also known as heterogeneous nuclear ribonucleoprotein L-like, plays a crucial role in post-transcriptional regulation of gene expression by influencing mRNA splicing and stability.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
HNRPLL Antibody
SKU:
CAB10360
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SRRF, HNRPLL
Positive Sample:
A-549, DU145, HepG2, 293T, Mouse liver
Cellular Localization:
Nucleus, Synapse.
Calculated MW:
60kDa
Observed MW:
60kDa
HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).
Purification Method
Affinity purification
Gene ID
92906
RRID
AB_2757906
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using HNRPLL Rabbit pAb (CAB10360) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
