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GenieFluor 488 Anti-Human CD11b Antibody [ICRF44] (AGEL1757)

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SKU AGEL1757
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Host Species Mouse
Isotype IgG2a,k
Clone ICRF44
Conjugation AF 488
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Description

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GenieFluor 488 Anti-Human CD11b Antibody [ICRF44]

The Human CD11b Monoclonal Antibody (AF488 Conjugated) - ICRF44 (AGEL1757) offered by Assay Genie is a cutting-edge tool for researchers in the field of immunology and cell biology. This antibody specifically targets CD11b, a key cell surface marker for the identification and characterization of myeloid cells, particularly macrophages and granulocytes.The monoclonal antibody is conjugated with AF488, a highly fluorescent dye, allowing for precise visualization and tracking of CD11b-expressing cells in a variety of experimental settings. With the ICRF44 clone, this antibody is known for its high specificity and sensitivity to human CD11b, ensuring reliable and accurate results in flow cytometry, immunofluorescence, and other fluorescence-based applications.

By targeting CD11b, researchers can unravel crucial insights into immune responses, inflammation, and pathogenesis in conditions such as infections, autoimmune diseases, and cancer. The ability to detect and analyze human CD11b-expressing cells with precision makes this antibody an indispensable tool for investigating the role of myeloid cells in various disease states, ultimately paving the way for new therapeutic strategies and interventions.Enhance your research capabilities with the Human CD11b Monoclonal Antibody (AF488 Conjugated) - ICRF44 (AGEL1757) from Assay Genie and unlock the potential for groundbreaking discoveries in immunology and beyond.

Product Title:GenieFluor 488 Anti-Human CD11b Antibody [ICRF44]
SKU:AGEL1757
Size:20 Tests, 100 Tests, 200 Tests
Clone No:ICRF44
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 488 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11215
Gene ID:3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.

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