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GenieFluor 647 Anti-Human CD147 Antibody [HIM6] (AGEL0979)

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SKU AGEL0979
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Human
Host Species Mouse
Isotype IgG2a,k
Clone HIM6
Conjugation AF 647
€107 - €413
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Description

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GenieFluor 647 Anti-Human CD147 Antibody [HIM6]

The Human CD147 Monoclonal Antibody (AF647 Conjugated) HIM6 (AGEL0979) from AssayGenie is a cutting-edge tool for research involving CD147, a transmembrane glycoprotein known for its role in various physiological and pathological processes. This monoclonal antibody, conjugated with AF647, offers exceptional specificity and sensitivity in detecting CD147 expression in human samples.CD147, also referred to as EMMPRIN or basigin, is a multifaceted molecule involved in diverse cellular functions such as cell adhesion, migration, and signaling. It is particularly recognized for its involvement in cancer progression, inflammation, and tissue remodeling. The HIM6 antibody targets CD147 with high affinity, making it an invaluable asset for investigating the molecular mechanisms underlying these processes.With its fluorescent AF647 conjugation, this antibody enables precise visualization and quantification of CD147 expression in various cell types and tissues.

Its versatility extends to applications such as immunofluorescence, flow cytometry, and immunohistochemistry, providing researchers with a comprehensive toolkit for studying CD147 biology in health and disease.Researchers in fields like oncology, immunology, and cell biology can leverage the Human CD147 Monoclonal Antibody (AF647 Conjugated) HIM6 (AGEL0979) to unravel the intricate roles of CD147 in physiological pathways and pathological conditions. By gaining insights into CD147's functions, potential therapeutic targets may be identified, paving the way for innovative strategies in cancer treatment, inflammation modulation, and tissue regeneration.

Product Title:GenieFluor 647 Anti-Human CD147 Antibody [HIM6]
SKU:AGEL0979
Size:20 Tests, 100 Tests, 200 Tests
Clone No:HIM6
Synonyms:Basigin;BSG;5F7;Collagenase stimulatory factor;Extracellular matrix metalloproteinase inducer;EMMPRIN;Leukocyte activation antigen M6;OK blood group antigen;Tumor cell-derived collagenase stimulatory factor;TCSF;CD147;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Genie Fluor 647 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P35613
Gene ID:682
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD147, also known as neurothelin or basigin, is a member of the Ig superfamily. It is a 55-65 kD type I transmembrane glycoprotein which is primarily expressed on leukocytes, erythrocytes, platelets, and endothelial cells. CD147 is reported to have a function during embryonal brain development and/or play a role in integrin-mediated adhesion in brain endothelia.

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