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Purified Anti-Human CD58 Antibody [TS2/9.1] (AGEL0271)

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SKU AGEL0271
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Host Species Mouse
Isotype IgG1
Clone TS2/9.1
Conjugation Unconjugated
Applications FC
Applications IP
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Description

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Purified Anti-Human CD58 Antibody [TS2/9.1]

The Human CD58 Monoclonal Antibody (TS2/9.1) is a specialized research tool offered by AssayGenie for the study of CD58, a cell surface glycoprotein involved in immune cell interactions and signaling. This monoclonal antibody, produced using hybridoma technology, exhibits high specificity and sensitivity when detecting CD58 expression in human samples, making it an ideal choice for various experimental applications.CD58, also known as LFA-3 (lymphocyte function-associated antigen 3), plays a crucial role in immune responses by facilitating cell adhesion and activation. Its interaction with CD2 on T cells is essential for T cell activation and the formation of immunological synapses. Studying the expression and function of CD58 can provide valuable insights into immune system regulation, particularly in the context of adaptive immunity and inflammatory processes.

Researchers in immunology, cell biology, and infectious diseases can benefit from the use of the Human CD58 Monoclonal Antibody (TS2/9.1) for experiments such as flow cytometry, immunofluorescence, and immunohistochemistry. By accurately detecting CD58 expression and localization, this antibody enables detailed analysis of immune cell dynamics and interactions, contributing to a better understanding of immune responses in health and disease.Unlock the potential of your research with the Human CD58 Monoclonal Antibody (TS2/9.1) from AssayGenie. Trust in its reliability and specificity to advance your investigations into immune cell biology, immune-mediated diseases, and potential therapeutic targets associated with CD58 signaling pathways.

Product Title:Purified Anti-Human CD58 Antibody [TS2/9.1]
SKU:AGEL0271
Size:25µg, 100µg
Clone No:TS2/9.1
Synonyms:Lymphocyte function-associated antigen 3;CD58;Ag3;Surface glycoprotein LFA-3;LFA3;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P19256
Gene ID:965
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface.

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