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PE Anti-Human CD61 Antibody [VI-PL2] (AGEL1826)

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SKU AGEL1826
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Applications FC
€113 - €413
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Description

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PE Anti-Human CD61 Antibody [VI-PL2]

The Human CD61 Monoclonal Antibody (PE Conjugated) is a powerful tool for researchers studying cell surface marker CD61, which plays a key role in platelet aggregation and clot formation. This antibody, conjugated with phycoerythrin (PE), allows for easy detection and visualization of the CD61 protein in human samples using flow cytometry and other fluorescence-based techniques.CD61, also known as integrin beta 3, is a critical component of platelet function and is involved in various physiological processes, including hemostasis and wound healing.

Dysregulation of CD61 expression or function has been implicated in thrombotic disorders, vascular diseases, and certain types of cancer. By using this PE-conjugated monoclonal antibody, researchers can accurately assess CD61 expression levels in different cell populations, shedding light on its role in various disease states and paving the way for new therapeutic strategies targeting CD61.

Product Title:PE Anti-Human CD61 Antibody [VI-PL2]
SKU:AGEL1826
Size:20 Tests, 100 Tests, 200 Tests
Clone No:VI-PL2
Synonyms:GP3A;GPIIIa;ITGB3;Integrin beta-3;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05106
Gene ID:3690
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins.

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