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PerCP/Cyanine5.5 Anti-Human CD86 Antibody [BU63] (AGEL0650)

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SKU AGEL0650
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Applications FC
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Description

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PerCP/Cyanine5.5 Anti-Human CD86 Antibody [BU63]

The Human CD86 Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated) (BU63) is an essential tool for researchers studying the immune system. CD86, also known as B7-2, is a co-stimulatory molecule expressed on antigen-presenting cells that plays a key role in activating T cells and initiating immune responses. This monoclonal antibody, conjugated with PERCP-Cyanine5.5 for fluorescent detection, specifically targets human CD86, allowing for precise identification and analysis in flow cytometry and immunofluorescence applications.

By targeting CD86, researchers can investigate its role in immune activation, T cell function, and inflammation. This antibody provides crucial insights into the mechanisms underlying immune responses, making it valuable for studies in immunology, vaccine development, and autoimmune diseases. With its high specificity and sensitivity, the Human CD86 Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated) (BU63) is a valuable tool for advancing research in immunology and related fields.

Product Title:PerCP/Cyanine5.5 Anti-Human CD86 Antibody [BU63]
SKU:AGEL0650
Size:20 Tests, 100 Tests, 200 Tests
Clone No:BU63
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P42081
Gene ID:942
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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