The IFNG Antibody (CAB0242) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By targeting interferon gamma, this antibody enables researchers to detect and analyze its expression in various cell types, making it a valuable asset for immunology and infectious disease studies.Interferon gamma is a crucial mediator of immune defense, playing a role in activating immune cells, regulating the inflammatory response, and combating infections. Dysregulation of interferon gamma signaling has been linked to various diseases, including autoimmune disorders, infectious diseases, and inflammatory conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
IFNG Antibody
SKU:
CAB0242
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
IFG, IFI, IMD69, IFN gamma
Positive Sample:
Recombinant Human Interferon Gamma Protein
Cellular Localization:
Secreted.
Calculated MW:
19kDa
Observed MW:
17kDa
This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases.
Purification Method
Affinity purification
Gene ID
3458
RRID
AB_2757055
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of Recombinant Human IFN-gamma Protein (RP01038) using IFN gamma Rabbit pAb (CAB0242) at 1:2000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 10ng per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
