The IKKalpha Monoclonal Antibody (CAB19694) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced using rabbit monoclonal technology, exhibits high specificity and sensitivity in detecting IKKalpha in human samples, making it ideal for use in Western blot and immunohistochemistry applications.IKKalpha, also known as Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Alpha, plays a crucial role in regulating the expression of genes involved in inflammation, immunity, and cell survival. Dysregulation of IKKalpha activity has been implicated in various diseases, including cancer, inflammatory disorders, and autoimmune conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
IKKalpha Monoclonal Antibody
SKU:
CAB19694
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Clone Number:
ARC0174
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
Purification Method
Affinity purification
Gene ID
1147
RRID
AB_2862739
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using IKKα Rabbit mAb (CAB19694) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
