The IKKbeta Monoclonal Antibody (CAB19606) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and sensitivity for human samples and has been validated for use in Western blotting and immunohistochemistry applications.IKKbeta serves as a crucial mediator in the activation of NF-kappaB, a transcription factor that plays a central role in regulating various cellular processes, including immune responses and cell proliferation. Dysregulation of the NF-kappaB pathway is associated with a variety of diseases, such as cancer, autoimmune disorders, and inflammatory conditions.
This antibody is validated for use in IF/ICC, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
IKKbeta Monoclonal Antibody
SKU:
CAB19606
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC2632
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene.
Purification Method
Affinity purification
Gene ID
3551
RRID
AB_2862695
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Confocal imaging of HeLa cells using IKKβ Rabbit mAb (CAB19606,dilution 1:100)(Red). The cells were counterstained with α-Tubulin Mouse mAb (AC012,dilution 1:400) (Green). DAPI was used for nuclear staining (blue). Objective: 100x.
