The IL-37 Polyclonal Antibody (CAB8206) is a valuable tool for researchers studying IL-37, a member of the interleukin-1 family with potent anti-inflammatory properties. This antibody, raised in rabbits, demonstrates high reactivity with human samples and is validated for use in various applications, including Western blotting.IL-37 is known for its ability to suppress inflammation and regulate immune responses, making it a potential target for developing treatments for inflammatory conditions such as autoimmune diseases and chronic inflammation.
By detecting and analyzing the IL-37 protein in different cell types, researchers can gain insights into its role in immune regulation and potentially identify new therapeutic strategies.With its specificity and reliability, the IL-37 Polyclonal Antibody is a valuable tool for investigators studying the complex mechanisms of immune regulation and inflammation, paving the way for future advancements in therapeutics and disease management.
Product Name:
IL37 Rabbit Polyclonal Antibody
SKU:
CAB8206
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human IL37 (NP_055254.2).
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18. This gene along with eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.
Purification Method:
Affinity purification
Gene ID:
27178
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using IL37 Rabbit pAb (CAB8206) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 20s.
