The IRAK2 Antibody (CAB6635) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific to human IRAK2 samples and has been validated for use in Western blot applications.IRAK2, a member of the interleukin-1 receptor-associated kinase (IRAK) family, plays a crucial role in the activation of inflammatory responses and the regulation of immune signaling. Dysregulation of IRAK2 has been implicated in various diseases, including autoimmune disorders, inflammation, and cancer.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
IRAK2 Antibody
SKU:
CAB6635
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
IRAK-2, IRAK2
Positive Sample:
A-549, HeLa, HepG2, NCI-H460, Mouse liver, Mouse kidney, Rat lung
Cellular Localization:
Cytoplasm, Cytosol, Nucleus, Plasma Membrane.
Calculated MW:
69kDa
Observed MW:
75kDa
IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB.
Purification Method
Affinity purification
Gene ID
3656
RRID
AB_2767224
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using IRAK2 Rabbit pAb (CAB6635) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
