The IRAK4 Monoclonal Antibody (CAB20839) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting IRAK4 in human samples. It has been validated for use in Western blot applications, enabling researchers to analyze IRAK4 expression levels in various cell types and tissues.IRAK4, or interleukin-1 receptor-associated kinase 4, is essential for initiating immune responses to pathogens and plays a crucial role in inflammatory processes.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
IRAK4 Monoclonal Antibody
SKU:
CAB20839
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC51289
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
51135
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from wild type(WT) and IRAK4 knockdown (KD) 293T cells, using [KD Validated] IRAK4 Rabbit mAb (CAB20839) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
