The ITPR3 Monoclonal Antibody (CAB23202) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is designed for use in various research applications, including immunofluorescence, immunohistochemistry, and Western blotting, allowing for reliable detection and analysis of ITPR3 expression in cell and tissue samples.ITPR3 is known to play a crucial role in regulating calcium release from intracellular stores, which is essential for various cellular processes like cell proliferation, differentiation, and apoptosis.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
ITPR3 Monoclonal Antibody
SKU:
CAB23202
Size:
20μL, 100μL
Reactivity:
Human
Clone Number:
ARC59549
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:2000 - 1:6000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.
Purification Method
Affinity purification
Gene ID
3710
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using ITPR3 Rabbit mAb (CAB23202) at 1:5000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
