The KBTBD8 Antibody (CAB18513) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting KBTBD8 in human samples, making it suitable for applications such as Western blot analysis.KBTBD8 is a substrate-specific adaptor protein that plays a role in the ubiquitin-proteasome system, which regulates protein turnover and degradation within cells. Dysregulation of this system can lead to the development of various diseases, including cancer and neurodegenerative disorders.
This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
KBTBD8 Antibody
SKU:
CAB18513
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
TAKRP, TA-KRP, KBTBD8
Positive Sample:
Rat lung
Cellular Localization:
Cytosol, Golgi Apparatus, Spindle.
Calculated MW:
69kDa
Observed MW:
69kDa
Involved in neural crest cell development; neural crest formation; and protein monoubiquitination. Part of Cul3-RING ubiquitin ligase complex.
Purification Method
Affinity purification
Gene ID
84541
RRID
AB_2862277
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat lung, using KBTBD8 Rabbit pAb (CAB18513) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
