The KDM1A Polyclonal Antibody is a valuable tool for researchers studying the role of KDM1A, a key enzyme involved in gene regulation and chromatin remodeling. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications.KDM1A, also known as Lysine-specific demethylase 1A, plays a crucial role in the epigenetic regulation of gene expression by removing methyl groups from lysine residues on histone proteins. This process impacts various cellular functions and pathways, making KDM1A a significant target for research in cancer, neurodegenerative diseases, and stem cell biology.
By specifically binding to the KDM1A protein, this antibody enables researchers to detect and analyze its expression levels in different cell types and tissue samples. Its versatility and reliability make it an ideal choice for scientists investigating the molecular mechanisms of epigenetic regulation and its implications in various disease states.
Product Name:
KDM1A Polyclonal Antibody
SKU:
CAB21801
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 130-380 of human KDMIA (NP_055828.2).
This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
23028
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using KDM1A Rabbit pAb (CAB21801) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 20s.
