The Kitlg Polyclonal Antibody (CAB16245) is a valuable tool for researchers studying the Kitlg protein, also known as stem cell factor or hematopoietic growth factor. Kitlg is a cytokine that plays a crucial role in the regulation of stem cell proliferation and differentiation, making it a key player in processes such as hematopoiesis and melanogenesis.Produced in rabbits, this antibody is highly specific to Kitlg and has been validated for use in various applications, including Western blotting and immunohistochemistry. Its ability to detect and bind to the Kitlg protein makes it an essential tool for studying cellular processes involving stem cell regulation and differentiation.
Research on Kitlg is important in the fields of developmental biology, cancer biology, and regenerative medicine. By understanding the role of Kitlg in various physiological and pathological conditions, researchers can develop targeted therapies for diseases such as leukemia, mast cell disorders, and certain types of cancer that are influenced by abnormal Kitlg signaling pathways. Overall, the Kitlg Polyclonal Antibody (CAB16245) is a reliable and sensitive reagent that can enhance your research efforts in unraveling the complexities of stem cell biology and its implications in health and disease.
Product Name:
KITLG Rabbit Polyclonal Antibody
SKU:
CAB16245
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-214 of human KITLG (NP_000890.1).
Cell membrane, Cytoplasm, Secreted, Single-pass type I membrane protein, cytoskeleton.
Calculated MW:
31kDa
Observed MW:
31kDa
This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4254
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of mouse brain, using KITLG antibody (CAB16245) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
