The LARP1 Antibody (CAB4543) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding to the LARP1 protein, this antibody allows for the detection and analysis of LARP1 in various cell types, making it ideal for studies in molecular biology and cancer research.LARP1, also known as La-related protein 1, plays a crucial role in the regulation of mRNA metabolism and is implicated in various cellular processes such as cell proliferation and differentiation.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
LARP1 Antibody
SKU:
CAB4543
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
LARP, Lar1, Lhp1, LARP1
Positive Sample:
HeLa, MCF7
Cellular Localization:
Cytoplasm.
Calculated MW:
124kDa
Observed MW:
163kDa
Enables eukaryotic initiation factor 4E binding activity; nucleic acid binding activity; and ribosomal small subunit binding activity. Involved in several processes, including TORC1 signaling; cellular response to rapamycin; and posttranscriptional regulation of gene expression. Located in cytoplasmic stress granule. Colocalizes with TORC1 complex and polysomal ribosome.
Purification Method
Affinity purification
Gene ID
23367
RRID
AB_2765744
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using LARP1 Rabbit pAb (CAB4543) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 90s.
