The LLGL2 Polyclonal Antibody (CAB8284) is specifically designed for research involving LLGL2, a protein that plays a key role in cell polarity and cell division. This antibody, generated in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. It binds to the LLGL2 protein, allowing for precise detection and analysis in various cell types, making it ideal for studies focused on cell biology and cancer research.LLGL2, also known as lethal giant larvae homolog 2, is essential for maintaining cell polarity and regulating cell growth and division.
Dysfunction of LLGL2 has been linked to various types of cancer, making it a potential target for therapeutic interventions. By studying the function of LLGL2, researchers can gain valuable insights into cancer progression and potentially develop novel treatment strategies targeting this protein.Overall, the LLGL2 Polyclonal Antibody (CAB8284) is a valuable tool for researchers conducting studies on cell polarity, cell division, and cancer biology. Its high reactivity and specificity make it a reliable choice for investigating the role of LLGL2 in various cellular processes and disease states.
Product Name:
LLGL2 Rabbit Polyclonal Antibody
SKU:
CAB8284
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 620-819 of mouse LLGL2 (NP_663413.2).
Predicted to enable GTPase activator activity; PDZ domain binding activity; and myosin II binding activity. Acts upstream of or within establishment or maintenance of polarity of embryonic epithelium; labyrinthine layer development; and post-embryonic development. Predicted to be located in cytosol and intracellular membrane-bounded organelle. Predicted to be active in cortical actin cytoskeleton and plasma membrane. Is expressed in several structures, including cardiovascular system; endocrine gland; genitourinary system; gut; and nasal cavity epithelium. Orthologous to human LLGL2 (LLGL scribble cell polarity complex component 2).
Purification Method:
Affinity purification
Gene ID:
217325
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using LLGL2 antibody (CAB8284) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 5s.
