Description
LXN Antibody (PACO47514)
The LXN Antibody (PAC047514) is a powerful tool for researchers studying LXN, a protein linked to immune regulation and cancer development. This polyclonal antibody, derived from rabbit serum, exhibits strong reactivity with LXN in human samples and is validated for use in Western blot applications. By specifically binding to LXN, researchers can easily detect and analyze this protein in various cell types, making it ideal for studies in immunology and oncology.LXN, also known as relaxin, has been shown to play a role in immune system modulation and has been implicated in the progression of certain cancers.
Understanding the function of LXN is crucial for uncovering its potential as a therapeutic target for cancer treatment and immune-related disorders. By using the LXN Antibody, researchers can gain valuable insights into the role of LXN in these disease contexts and potentially develop new strategies for therapeutic intervention.
| Antibody Name: | LXN Antibody (PACO47514) |
| Antibody SKU: | PACO47514 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Latexin protein (1-216AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human appendix tissue using PACO47514 at dilution of 1:100. |
 | Immunofluorescent analysis of Hela cells using PACO47514 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation. |
| Synonyms: | Latexin (Endogenous carboxypeptidase inhibitor) (ECI) (Protein MUM) (Tissue carboxypeptidase inhibitor) (TCI), LXN |
| UniProt Protein Function: | LXN: Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. Belongs to the protease inhibitor I47 (latexin) family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 3q25.32 Molecular Function:protein binding |
| NCBI Summary: | This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. [provided by RefSeq, Oct 2008] |
| UniProt Code: | Q9BS40 |
| NCBI GenInfo Identifier: | 146345452 |
| NCBI Gene ID: | 56925 |
| NCBI Accession: | Q9BS40.2 |
| UniProt Secondary Accession: | Q9BS40,Q96PN2, Q9NQS6, |
| UniProt Related Accession: | Q9BS40 |
| Molecular Weight: | 25,750 Da |
| NCBI Full Name: | Latexin |
| NCBI Synonym Full Names: | latexin |
| NCBI Official Symbol: | LXNÂ Â |
| NCBI Official Synonym Symbols: | ECI; TCIÂ Â |
| NCBI Protein Information: | latexin |
| UniProt Protein Name: | Latexin |
| UniProt Synonym Protein Names: | Endogenous carboxypeptidase inhibitor; ECI; Protein MUM; Tissue carboxypeptidase inhibitor; TCI |
| Protein Family: | Latexin |
| UniProt Gene Name: | LXNÂ Â |
| UniProt Entry Name: | LXN_HUMAN |
