The Magee1 Polyclonal Antibody (PAC019977) is a valuable tool for researchers studying CD300A, an important immune regulatory molecule. This antibody, produced in rabbits, is highly specific for human samples and has been validated for Western blot applications. By binding to the CD300A protein, this antibody allows for the detection and analysis of CD300A in various cell types, making it an ideal reagent for studies in immunology and cancer research.CD300A, also known as an immune inhibitory receptor, plays a key role in immune regulation by suppressing immune responses and maintaining immune homeostasis.
Understanding the function of CD300A is essential for investigating diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions, where dysregulation of the immune system is implicated. The Magee1 Polyclonal Antibody provides researchers with a reliable tool to explore the role of CD300A in these diseases and may aid in the development of novel therapeutic strategies targeting immune modulation.
Antibody Name:
MAGEE1 Antibody (PACO19977)
Antibody SKU:
PACO19977
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human MAGEE1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO19977(MAGEE1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19977(MAGEE1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene encodes an alpha-dystrobrevin-associated MAGE (melanoma-associated antigen) protein, which is a member of the MAGE family. The protein contains a nuclear localization signal in the N-terminus, 30 12-amino acid, repeats beginning at nt 60 with the consensus sequence ASEGPSTSVLPT, and two MAGE domains in the C-terminus. It may play a signaling role in brain, muscle, and peripheral nerve. This gene is located on X chromosome in a region containing loci linked to mental retardation.
