The MEGF8 Polyclonal Antibody (PACO00740) is a research tool designed for studying MEGF8, a protein involved in various cellular processes including cell adhesion and signaling. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting MEGF8, researchers can study its function in different cell types and gain insights into its role in cellular pathways.MEGF8 is a multi-domain protein that plays a crucial role in several developmental processes, including neural tube closure and skeletal development.
Dysregulation of MEGF8 has been linked to developmental disorders and skeletal abnormalities, making it a promising target for further investigation in the fields of developmental biology and genetics. By using the MEGF8 Polyclonal Antibody, researchers can explore the function of MEGF8 and its implications in various biological processes.
Antibody Name:
MEGF8 Antibody
Antibody SKU:
PACO00740
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human EGFL4.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
MEGF8; C19orf49; EGFL4; KIAA0817; Multiple epidermal growth factor-like domains protein 8; Multiple EGF-like domains protein 8; Epidermal growth factor-like protein 4; EGF-like protein 4
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a single-pass type I membrane protein of unknown function that contains several EGF-like domains, Kelch repeats, and PSI domains. Defects in this gene are a cause of Carpenter syndrome 2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
