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MMP28 Antibody (PACO10526)

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SKU:
PACO10526
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
$551

Description

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MMP28 Antibody (PACO10526)

The MMP28 Polyclonal Antibody (PACO10526) is a valuable tool for researchers studying matrix metalloproteinase 28 (MMP28), a member of the matrix metalloproteinase family known for its role in extracellular matrix remodeling and tissue remodeling processes. Raised in rabbits, this antibody is highly specific to human MMP28 and has been validated for use in Western blot applications. By binding to MMP28 protein, this antibody allows for the detection and analysis of MMP28 expression in various cell types, making it an essential tool for studies in cancer metastasis, tissue regeneration, and wound healing research.MMP28 is a protease enzyme that plays a crucial role in the degradation of extracellular matrix components, cell migration, and tissue remodeling.

Its dysregulation has been linked to various pathological conditions, including cancer progression, arthritis, and cardiovascular diseases. By understanding the functions and regulation of MMP28, researchers can potentially develop targeted therapies for these diseases by modulating its activity.Overall, the MMP28 Polyclonal Antibody (PACO10526) is a valuable resource for researchers looking to investigate the role of MMP28 in physiological and pathological processes, providing insights that could lead to the development of novel therapeutic strategies.

Antibody Name:MMP28 Antibody (PACO10526)
Antibody SKU:PACO10526
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human MMP28
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:matrix metallopeptidase 28;MMP28;EPILYSIN;MM28;MMP-28;MMP25 ;
UniProt Protein Function:MMP28: Can degrade casein. Could play a role in tissues homeostasis and repair. Belongs to the peptidase M10A family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Protease; EC 3.4.24.-; Secreted; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: proteinaceous extracellular matrix; cytoplasm

Molecular Function:zinc ion binding; metalloendopeptidase activity; calcium ion binding

Biological Process: proteolysis

NCBI Summary:Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
UniProt Code:Q9H239
NCBI GenInfo Identifier:37538314
NCBI Gene ID:79148
NCBI Accession:Q9H239.2
UniProt Secondary Accession:Q9H239,Q96F04, Q96TE2,
UniProt Related Accession:Q9H239
Molecular Weight:520
NCBI Full Name:Matrix metalloproteinase-28
NCBI Synonym Full Names:matrix metallopeptidase 28
NCBI Official Symbol:MMP28  
NCBI Official Synonym Symbols:MM28; MMP25; MMP-25; MMP-28; EPILYSIN  
NCBI Protein Information:matrix metalloproteinase-28; matrix metalloprotease MMP25
UniProt Protein Name:Matrix metalloproteinase-28
UniProt Synonym Protein Names:Epilysin
Protein Family:Matrix metalloproteinase
UniProt Gene Name:MMP28  
UniProt Entry Name:MMP28_HUMAN

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