The Mouse CD106 Monoclonal Antibody (AF488 Conjugated, M/K-2.7) is a powerful tool for researchers studying CD106, a cell adhesion molecule involved in inflammation and immune responses. This monoclonal antibody, conjugated with AF488 for fluorescence applications, specifically targets CD106 in mouse samples, offering reliable detection and analysis in various experimental settings.CD106, also known as vascular cell adhesion molecule-1 (VCAM-1), plays a key role in the recruitment and activation of immune cells during inflammatory processes. By targeting CD106, researchers can investigate its involvement in diseases such as atherosclerosis, autoimmune disorders, and inflammatory conditions.
Understanding the expression and function of CD106 is essential for developing targeted therapies that modulate immune responses and inflammation.The Mouse CD106 Monoclonal Antibody (AF488 Conjugated, M/K-2.7) provides a valuable tool for studying the mechanisms of immune cell adhesion and migration in different physiological and pathological conditions. Its specificity and fluorescent conjugation make it suitable for applications such as flow cytometry, immunofluorescence, and immunohistochemistry, advancing research in immunology, vascular biology, and related fields.
Vascular cell adhesion protein 1;Vcam1;V-CAM 1;VCAM-1;CD106;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG1, κ
Isotype Control:
Genie Fluor 488 Rat IgG1, κ Isotype Control[HRPN]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P29533
Gene ID:
22329
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).
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