The Mouse CD106 Monoclonal Antibody (AF647 Conjugated) is a powerful tool for researchers studying CD106, a cell surface molecule known for its role in immune response modulation. This antibody, designated as M-K-2.7 (AGEL1171), is specifically designed for experiments involving CD106 and is conjugated with AF647 for effective detection and analysis.CD106, also known as vascular cell adhesion molecule-1 (VCAM-1), plays a crucial role in mediating leukocyte adhesion and recruitment during inflammatory responses. By targeting CD106 with this monoclonal antibody, researchers can examine its expression and function in different cell types, making it an ideal choice for studies in immunology, inflammation, and vascular biology.
With its high specificity and reactivity, the Mouse CD106 Monoclonal Antibody (AF647 Conjugated) offers a reliable tool for investigating the role of CD106 in various biological processes. Whether exploring immune cell interactions, inflammatory pathways, or vascular dynamics, this antibody provides valuable insights that can advance our understanding of immune-related diseases and potential therapeutic interventions.
Vascular cell adhesion protein 1;Vcam1;V-CAM 1;VCAM-1;CD106;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG1, κ
Isotype Control:
Genie Fluor 647 Rat IgG1, κ Isotype Control[HRPN]
Form:
Liquid
Conjugation:
Genie Fluor647
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P29533
Gene ID:
22329
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).
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