The Mouse CD106 Monoclonal Antibody PE/Cyanine5 Conjugated (M-K-2.7) is a specialized tool for researchers studying CD106, a cell adhesion molecule involved in immune responses and inflammation. This antibody is derived from mouse cells and is conjugated with PE/Cyanine5 for detection and analysis in flow cytometry and related applications. By targeting the CD106 protein, this antibody enables precise identification and characterization of CD106-expressing cells, facilitating in-depth studies in immunology and related fields.CD106, also known as vascular cell adhesion molecule-1 (VCAM-1), plays a key role in the immune response by mediating cell adhesion and migration.
Its involvement in inflammatory processes, particularly in the recruitment of immune cells to sites of infection or tissue damage, makes it a valuable target for research into conditions such as inflammatory diseases, atherosclerosis, and transplant rejection. Investigating the function and regulation of CD106 with this antibody can provide valuable insights into the immune mechanisms underlying these conditions, potentially leading to the development of targeted therapeutic strategies.
Product Title:
PE/Cyanine5 Anti-Mouse CD106 Antibody [M/K-2.7]
SKU:
AGEL1175
Size:
25µg, 100µg
Clone No:
M/K-2.7
Synonyms:
Vascular cell adhesion protein 1;Vcam1;V-CAM 1;VCAM-1;CD106;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG1, κ
Isotype Control:
PE/Cyanine5 Rat IgG1, κ Isotype Control[HRPN]
Form:
Liquid
Conjugation:
PE/Cyanine 5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P29533
Gene ID:
22329
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).
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