The Mouse CD106 Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated, M/K-2.7) is a high-quality antibody developed for research purposes related to CD106, a cell adhesion molecule involved in inflammation and immune response regulation. This antibody is derived from mouse monoclonal sources and is specifically conjugated with PerCP-Cyanine5.5 for enhanced detection capabilities.CD106, also known as vascular cell adhesion molecule-1 (VCAM-1), plays a vital role in immune cell recruitment and adhesion processes within the body. It is a key player in inflammatory responses and can influence various disease states, including autoimmune disorders, atherosclerosis, and inflammatory conditions.
Researchers can utilize this antibody in flow cytometry and related experimental techniques to analyze the expression and function of CD106 in different cell types and biological contexts. By targeting CD106 with this specific antibody, scientists can gain valuable insights into the mechanisms underlying immune responses and inflammatory pathways, paving the way for potential therapeutic interventions and treatments.Overall, the Mouse CD106 Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated, M/K-2.7) is a valuable tool for investigating the role of CD106 in immunology, inflammation, and disease, offering precise and reliable detection for cutting-edge research endeavors.
Vascular cell adhesion protein 1;Vcam1;V-CAM 1;VCAM-1;CD106;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG1, κ
Isotype Control:
PerCP/Cyanine5.5 Rat IgG1, κ Isotype Control[HRPN]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P29533
Gene ID:
22329
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).
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