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GenieFluor 488 Anti-Mouse CD127/IL-7RA Antibody [A7R34] (AGEL0132)

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SKU AGEL0132
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Host Species Rat
Isotype IgG2a
Clone A7R34
Conjugation AF 488
Applications FC
€123 - €344
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Description

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GenieFluor 488 Anti-Mouse CD127/IL-7RA Antibody [A7R34]

The Mouse CD127 Monoclonal Antibody (ALEXA FLUOR 488 Conjugated, A7R34) is a cutting-edge tool designed for research in immunology and cell biology. This antibody specifically targets CD127, a cell surface marker also known as IL-7 receptor alpha chain, which plays a crucial role in immune cell development and function.Raised against mouse samples, this antibody is highly reactive and specifically binds to CD127, allowing for precise detection and analysis in various cell types. The ALEXA FLUOR 488 conjugation provides bright and stable fluorescence, making it ideal for flow cytometry and immunofluorescence applications.

CD127 is a key player in regulating T cell development, survival, and homeostasis, making it a significant target for studying immune responses, inflammation, and autoimmune diseases. By utilizing this monoclonal antibody, researchers can gain valuable insights into the role of CD127 in various biological processes, contributing to advancements in immunotherapy and understanding immune system disorders.

Product Title:GenieFluor 488 Anti-Mouse CD127/IL-7RA Antibody [A7R34]
SKU:AGEL0132
Size:50 Tests, 100 Tests, 200 Tests
Clone No:A7R34
Synonyms:Interleukin-7 receptor subunit alpha;Il7r;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;CD127;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:Genie Fluor488
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P16872
Gene ID:16197
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.

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