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PerCP/Cyanine5.5 Anti-Mouse CD161/NK1.1 Antibody [PK136] (AGEL0482)

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SKU AGEL0482
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Mouse
Isotype IgG2a,k
Clone PK136
Conjugation PerCP/Cy5.5
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Description

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PerCP/Cyanine5.5 Anti-Mouse CD161/NK1.1 Antibody [PK136]

The Mouse CD161/NK1.1 Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated, PK136) available at www.assaygenie.com is a powerful tool for researchers studying natural killer (NK) cells and T cell subsets in mouse models. This monoclonal antibody specifically targets the CD161/NK1.1 antigen, which is a cell surface marker associated with NK cells and some T cell populations.NK cells are central players in the innate immune response, with the ability to detect and eliminate infected or abnormal cells. The CD161/NK1.1 marker is commonly used to identify and study these cytotoxic lymphocytes, providing insights into their role in immune surveillance, infection, and anti-tumor immunity. Moreover, this antibody is conjugated with PerCP-Cyanine5.5, a fluorescent dye that enables easy detection and quantification of CD161/NK1.

1-expressing cells by flow cytometry and other fluorescence-based techniques.Researchers in immunology, oncology, and infectious diseases can leverage the Mouse CD161/NK1.1 Monoclonal Antibody to explore the function and behavior of NK cells in various experimental settings. By understanding the activation, differentiation, and effector functions of NK cell subsets marked by CD161/NK1.1, scientists can further unravel the complexities of the immune system and potentially discover novel therapeutic targets for immune-related diseases.For high-quality and reliable results in mouse NK cell research, the Mouse CD161/NK1.1 Monoclonal Antibody (PerCP-Cyanine5.5 Conjugated, PK136) from Assay Genie is an invaluable resource that promises specificity, sensitivity, and reproducibility in your studies.

Product Title:PerCP/Cyanine5.5 Anti-Mouse CD161/NK1.1 Antibody [PK136]
SKU:AGEL0482
Size:50 Tests, 100 Tests, 200 Tests
Clone No:PK136
Synonyms:Killer cell lectin-like receptor subfamily B member 1C;Klrb1c;CD161 antigen-like family member C;Ly-55c;CD161/NK1.1;NKR-P1.9;NKR-P1C;NKR-P1 40;CD161c;
Host Species:Mouse
Reactivity:Mouse
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:PerCP/Cyanine5.5 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P27814 P27812 Q99JB4
Gene ID:17059
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

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