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PerCP/Cyanine5.5 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173] (AGEL1426)

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SKU AGEL1426
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Armenian Hamster
Isotype IgG2a,k
Clone CXCR3-173
Conjugation PerCP/Cy5.5
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Description

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PerCP/Cyanine5.5 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]

The CXCR3 Monoclonal Antibody (PERCP-Cyanine5.5 conjugated) is a valuable tool for researchers studying the CXCR3 protein, a chemokine receptor involved in immune response and inflammation. This antibody, produced through monoclonal techniques, is specifically designed for the detection and analysis of CXCR3 in mouse samples. Its PERCP-Cyanine5.5 conjugation allows for efficient detection and quantification using flow cytometry, making it ideal for a wide range of immunology and inflammation studies.CXCR3 is known to play a crucial role in directing immune cell migration to sites of inflammation and infection.

Its dysregulation has been linked to various inflammatory conditions, autoimmune diseases, and cancer progression. By targeting and analyzing CXCR3 expression with this monoclonal antibody, researchers can gain valuable insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets. Overall, the CXCR3 Monoclonal Antibody offers a powerful tool for advancing research in immunology and related fields.

Product Title:PerCP/Cyanine5.5 Anti-Mouse CD183/CXCR3 Antibody [CXCR3-173]
SKU:AGEL1426
Size:50 Tests, 100 Tests, 200 Tests
Clone No:CXCR3-173
Synonyms:C-X-C chemokine receptor type 3;Cxcr3;CXC-R3;CXCR-3;Interferon-inducible protein 10 receptor;IP-10 receptor;CD183/CXCR3;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:PerCP/Cyanine5.5 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:O88410
Gene ID:12766
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

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