Description
| Product Name: | Mouse CD3?µ monoclonal antibody |
| Product Code: | AGIM0234 |
| Size: | 100 µg in 100 µL |
| Reactivity: | Mouse |
| Clone: | 145-2C11 |
| Applications: | Flow Cytometry |
| Conjugate: | Unconjugated |
| Isotype: | IgG |
| Host Species: | Hamster |
| Storage: | Stable at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Uniprot: | P22646 |
| UniProt Protein Function: | CD3E: a T cell surface glycoprotein that is a component of the T cell antigen receptor. The recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation. Contains 1 immunoglobulin-like domain and 1 ITAM domain. |
| UniProt Protein Details: | Protein type:Receptor, misc.; Membrane protein, integral Cellular Component: T cell receptor complex; membrane; integral to membrane; plasma membrane; immunological synapse; alpha-beta T cell receptor complex; intercellular junction; external side of plasma membrane Molecular Function:protein binding; signal transducer activity; transmembrane receptor activity; protein heterodimerization activity; SH3 domain binding Biological Process: positive regulation of interleukin-2 biosynthetic process; lymphocyte activation; positive regulation of calcium-mediated signaling; negative thymic T cell selection; T cell receptor signaling pathway; positive regulation of interleukin-4 production; positive regulation of interferon-gamma production; positive regulation of peptidyl-tyrosine phosphorylation; cell surface receptor linked signal transduction; negative regulation of smoothened signaling pathway; T cell costimulation; positive regulation of alpha-beta T cell proliferation; positive regulation of T cell proliferation; positive regulation of T cell activation; positive regulation of T cell anergy; response to nutrient |
| UniProt Code: | P22646 |
| NCBI GenInfo Identifier: | 6680886 |
| NCBI Gene ID: | 12501 |
| NCBI Accession: | NP_031674.1 |
| UniProt Related Accession: | P22646 |
| Molecular Weight: | 21,393 Da |
| NCBI Full Name: | T-cell surface glycoprotein CD3 epsilon chain |
| NCBI Synonym Full Names: | CD3 antigen, epsilon polypeptide |
| NCBI Official Symbol: | Cd3e  |
| NCBI Official Synonym Symbols: | CD3; T3e; AI504783; CD3epsilon  |
| NCBI Protein Information: | T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain |
| UniProt Protein Name: | T-cell surface glycoprotein CD3 epsilon chain |
| UniProt Synonym Protein Names: | T-cell surface antigen T3/Leu-4 epsilon chain; CD_antigen: CD3e |
| Protein Family: | CD302 antigen |
| UniProt Gene Name: | Cd3e  |
| UniProt Entry Name: | CD3E_MOUSE |
