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PerCP/Cyanine5.5 Anti-Mouse CD3 Antibody [17A2] (AGEL0662)

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SKU AGEL0662
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone 17A2
Conjugation PerCP/Cy5.5
€120 - €285
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Description

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PerCP/Cyanine5.5 Anti-Mouse CD3 Antibody [17A2]

The Mouse CD3 Monoclonal Antibody PerCP/Cyanine5.5 Conjugated (17A2) is a powerful tool for researchers studying immune responses in mice. This antibody is specifically designed to target CD3, a crucial marker for T cells, aiding in the detection and analysis of T cell activation and function.The 17A2 antibody, conjugated to PerCP/Cyanine5.5, offers the advantage of multiparametric flow cytometry analysis, allowing for the simultaneous detection of multiple markers in a single sample. This feature is especially valuable for investigating complex immune responses and cell populations in vivo and in vitro.CD3 is an essential component of the T cell receptor complex, playing a central role in antigen recognition and T cell activation.

By targeting CD3 with this monoclonal antibody, researchers can gain insights into T cell behavior, function, and regulation in various experimental settings including immunology studies, infectious disease research, and autoimmune disorder investigations.Utilizing the Mouse CD3 Monoclonal Antibody PerCP/Cyanine5.5 Conjugated (17A2) opens up opportunities for detailed characterization of T cell responses, paving the way for deeper understanding of immune processes and potentially leading to the development of novel therapeutic strategies for immune-related diseases.

Product Title:PerCP/Cyanine5.5 Anti-Mouse CD3 Antibody [17A2]
SKU:AGEL0662
Size:25µg, 100µg
Clone No:17A2
Synonyms:T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PerCP/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P04235 P11942 P22646 P24161
Gene ID:12502
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

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