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APC Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL0143)

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SKU AGEL0143
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Host Species Rat
Isotype IgG2a
Clone FGK4.5/FGK45
Conjugation APC
Applications FC
€82 - €200
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Description

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APC Anti-Mouse CD40 Antibody [FGK4.5/FGK45]

The Mouse CD40 Monoclonal Antibody (APC Conjugated, FGK4.5) is a powerful tool for researchers studying immune responses and cell signaling pathways involving CD40. This antibody, manufactured by Assay Genie, is specifically designed for flow cytometry applications and is validated for use in various experimental settings.CD40 is a cell surface receptor that plays a key role in the immune system, particularly in regulating B cell function and promoting antigen presentation. The APC-conjugated FGK4.5 antibody binds specifically to the CD40 protein, allowing for precise detection and analysis of CD40 expression on cell membranes. This makes it an essential reagent for investigating immune responses, inflammation, and the development of therapeutic strategies targeting CD40 signaling pathways.

By utilizing the Mouse CD40 Monoclonal Antibody (APC Conjugated, FGK4.5) in your research, you can gain valuable insights into the role of CD40 in immune regulation, autoimmunity, and infectious diseases. Whether you are studying immune cell activation, vaccine development, or immune checkpoint inhibitors, this antibody provides a reliable and accurate tool for your experiments. Trust Assay Genie's expertise in antibody development to support your research efforts and advance our understanding of CD40 biology.

Product Title:APC Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
SKU:AGEL0143
Size:50 Tests, 100 Tests, 200 Tests
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:APC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P27512
Gene ID:21939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

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