The Mouse CD45.2 Monoclonal Antibody (APC-conjugated, 104-2) (AGE1527) offered by AssayGenie is a powerful tool for researchers studying immune cell populations in mouse models. This antibody specifically targets the CD45.2 protein, a well-known marker for leukocytes, particularly T and B cells, in the immune system. The APC conjugation provides a fluorescent signal for easy detection and visualization in flow cytometry experiments, allowing for precise identification and analysis of CD45.2-positive cells.With its high specificity and sensitivity, this monoclonal antibody is ideal for immunophenotyping studies, cell subset identification, and assessing immune responses in mouse models of disease.
Whether investigating immune cell dynamics in cancer, inflammation, infection, or autoimmune conditions, the Mouse CD45.2 Monoclonal Antibody (APC-conjugated, 104-2) is a reliable tool for accurate and reproducible results. Trust AssayGenie's expertise in providing high-quality antibodies for your immunology research needs.
Product Title:
APC Anti-Mouse CD45.2 Antibody [104.2]
SKU:
AGEL1527
Size:
25µg, 100µg
Clone No:
104.2
Synonyms:
Ly-5.2; LCA;
Host Species:
Mouse
Reactivity:
Mouse
Application:
FCM
Isotype:
Mouse IgG2a, κ
Isotype Control:
APC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
19264
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
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