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FITC Anti-Mouse CD45.2 Antibody [104.2] (AGEL1525)

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SKU AGEL1525
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Mouse
Isotype IgG2a,k
Clone 104.2
Conjugation FITC
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Description

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FITC Anti-Mouse CD45.2 Antibody [104.2]

The Mouse CD45.2 Monoclonal Antibody (FITC conjugated) 104-2 (AGEL1525) is a vital tool designed for research involving the CD45.2 antigen, a key cell surface marker involved in immune cell signaling and activation. This monoclonal antibody, conjugated with FITC for fluorescent detection, is specifically targeted towards mouse samples and has been rigorously validated for use in flow cytometry applications.CD45.2, also known as leukocyte common antigen, is essential for T and B cell development and function. Its expression on immune cells allows for the identification and characterization of different immune cell populations.

This antibody binds specifically to CD45.2, enabling precise detection and analysis in diverse experimental settings, making it ideal for immunology and cell biology studies.Understanding the role of CD45.2 in immune cell signaling and function is crucial for unraveling the complexities of the immune system and its response to various stimuli. This antibody provides researchers with a reliable tool to investigate the expression and localization of CD45.2 in different immune cell populations, aiding in the advancement of research in immunology, inflammation, and autoimmune diseases.

Product Title:FITC Anti-Mouse CD45.2 Antibody [104.2]
SKU:AGEL1525
Size:25µg, 100µg
Clone No:104.2
Synonyms:Ly-5.2; LCA;
Host Species:Mouse
Reactivity:Mouse
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:FITC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Gene ID:19264
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

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