The Mouse CD5 Monoclonal Antibody FITC Conjugated (53-7.3) (AGEL1960) is a specialized research tool designed for the detection and analysis of CD5, a cell surface molecule known for its involvement in immune responses. This monoclonal antibody, conjugated with FITC for fluorescence detection, is specifically tailored for use in flow cytometry applications to study various cell types.CD5, a marker of mature T cells and B-1a B cells, plays a key role in the regulation of immune responses and is often implicated in autoimmune diseases and lymphoid malignancies. By targeting CD5 with this antibody, researchers can gain valuable insights into the expression and function of this important molecule in the immune system.
With its high specificity and reactivity to mouse samples, the Mouse CD5 Monoclonal Antibody FITC Conjugated (53-7.3) (AGEL1960) offers a reliable tool for immunology studies, particularly in the fields of B cell biology, T cell development, and autoimmune research. By enabling precise visualization and quantification of CD5-expressing cells, this antibody facilitates in-depth investigations into immune system dynamics and disease pathways, paving the way for innovative therapeutic interventions and treatment strategies.
Product Title:
FITC Anti-Mouse CD5 Antibody [53-7.3]
SKU:
AGEL1960
Size:
25µg, 100µg
Clone No:
53-7.3
Synonyms:
Ly-1;Lyt-1;Lymphocyte antigen 1;CD5;Cd5;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
FITC Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
FITC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P13379
Gene ID:
12507
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD5 is a 67 kD protein, also known as Lyt-1, Ly-1, T1, Tp67, or Ly-12. It is a member of the scavenger receptor cysteine-rich protein superfamily (SRCR) and primarily expressed on thymocytes, T cells, and B-1 cells. Although mature α/β T cells express high levels of CD5, very few γ/δ T cells express this antigen. The interaction of CD5 with CD72, gp35-37, TCR, or BCR is involved in T and B cell activation.
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