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FITC Anti-Mouse CD62L Antibody [Mel14] (AGEL0634)

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SKU AGEL0634
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone Mel14
Conjugation FITC
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Description

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FITC Anti-Mouse CD62L Antibody [Mel14]

The Mouse CD62L Monoclonal Antibody (FITC Conjugated, Mel-14) is a powerful tool for researchers studying immune responses and cell adhesion processes in mouse models. This antibody, produced by Assay Genie, specifically targets CD62L, a key cell surface molecule involved in lymphocyte homing and activation.The FITC conjugation of this monoclonal antibody enables easy visualization and detection in flow cytometry and immunofluorescence experiments. With its high specificity and sensitivity, researchers can confidently analyze CD62L expression on various cell types and investigate its role in immune cell migration and immune response modulation.

CD62L, also known as L-selectin, is crucial for the interaction between lymphocytes and endothelial cells during immune surveillance and inflammation. By targeting CD62L with this monoclonal antibody, researchers can gain insights into the mechanisms underlying immune cell trafficking and lymphocyte activation in health and disease.Ideal for studies in immunology, inflammation, and infectious diseases, the Mouse CD62L Monoclonal Antibody (FITC Conjugated, Mel-14) from Assay Genie is a valuable reagent for advancing research in immune system regulation and therapeutic interventions targeting lymphocyte function.

Product Title:FITC Anti-Mouse CD62L Antibody [Mel14]
SKU:AGEL0634
Size:25µg, 100µg
Clone No:Mel14
Synonyms:L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:FITC Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P18337
Gene ID:20343
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naïve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naïve, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.

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