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PerCP/Cyanine5.5 Anti-Mouse CD8a Antibody [53-6.7] (AGEL1343)

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SKU AGEL1343
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone 53-7.6
Conjugation PerCP/Cy5.5
€88 - €275
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Description

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PerCP/Cyanine5.5 Anti-Mouse CD8a Antibody [53-6.7]

The Mouse CD8a Monoclonal Antibody PerCP-Cyanine5.5 Conjugated (Clone 53-7.6) is a specialized tool for researchers studying immune cell biology, particularly focusing on CD8-positive T cells. This antibody, linked with the PerCP-Cyanine5.5 fluorophore, allows for accurate and sensitive detection of CD8a cell surface marker in flow cytometry and immunofluorescence applications.CD8a is a crucial marker for identifying cytotoxic T cells, a key component of the adaptive immune response. By targeting CD8a, researchers can precisely analyze and sort CD8-positive T cells in complex mixtures, aiding in the study of immune responses in various physiological and pathological conditions.

With its high specificity and sensitivity, the Mouse CD8a Monoclonal Antibody PerCP-Cyanine5.5 Conjugated (Clone 53-7.6) from Assay Genie provides researchers with a reliable tool to advance their understanding of T cell biology, immunotherapy, infectious diseases, and autoimmune disorders. Its ability to accurately detect CD8a expression levels in different cell populations makes it an indispensable resource for immunologists and cancer researchers aiming to unravel the complexities of the immune system.

Product Title:PerCP/Cyanine5.5 Anti-Mouse CD8a Antibody [53-6.7]
SKU:AGEL1343
Size:25µg, 100µg
Clone No:53-6.7
Synonyms:T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P01731
Gene ID:12525
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.

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