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Purified Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5] (AGEL0460)

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SKU AGEL0460
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Host Species Rat
Isotype IgG2b
Clone RB6-8C5
Conjugation Unconjugated
Applications FC
Applications WB
Applications IHC
Applications IP
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Description

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Purified Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]

The Mouse GR-1 Monoclonal Antibody (RB6-8C5) is a powerful tool for researchers investigating the immune system, specifically targeting the GR-1 protein expressed on the surface of certain immune cells. This antibody, produced through cutting-edge technology, is highly specific and has been validated for use in various experimental techniques, including flow cytometry and immunohistochemistry.GR-1, a marker for myeloid-derived suppressor cells (MDSCs) and neutrophils, plays a crucial role in regulating immune responses and inflammation. By targeting GR-1, researchers can better understand the function of these cells in conditions such as cancer, infection, and autoimmune diseases.

The ability to accurately detect and quantify GR-1 expression is essential for unraveling the complexities of the immune system and developing innovative therapeutic strategies.With its high affinity and sensitivity, the Mouse GR-1 Monoclonal Antibody (RB6-8C5) offers precise detection of GR-1-expressing cells in biological samples, providing valuable insights into immune cell dynamics and interactions. Whether studying immune cell populations in a tumor microenvironment or investigating inflammatory processes, this antibody is a valuable asset for researchers seeking to advance our understanding of immune regulation and pathology.

Product Title:Purified Anti-Mouse Ly-6G/Ly-6C (Gr-1) Antibody [RB6-8C5]
SKU:AGEL0460
Size:25µg, 100µg
Clone No:RB6-8C5
Synonyms:Gr-1;Gr1;Ly-6G/Ly-6C;Ly6G/Ly6C;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Purified Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.1 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P35461 P0CW03
Gene ID:546644 ,17067
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.

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