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PerCP Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114] (AGEL0502)

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SKU AGEL0502
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FC
Reactivity Mouse
Host Species Rat
Isotype IgG2a,k
Clone M5/114
Conjugation PerCP
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Description

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PerCP Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]

The Mouse MHC II (I-A/I-E) Monoclonal Antibody is a cutting-edge research tool offered by Assay Genie. This antibody, conjugated with PerCP, is specifically designed for the detection and analysis of Mouse Major Histocompatibility Complex Class II (MHC II) molecules I-A and I-E.MHC II molecules play a crucial role in the immune system by presenting antigens to T-cells, therefore initiating the adaptive immune response. The M5/114 antibody is a monoclonal antibody that targets I-A and I-E alleles, enabling researchers to study antigen presentation and T-cell activation in mouse models.

With its high specificity and sensitivity, this monoclonal antibody is an invaluable tool for immunology research, particularly in studies related to antigen presentation, T-cell activation, and immune responses in mouse models. Researchers can utilize this antibody in flow cytometry, immunofluorescence, and other experimental techniques to advance our understanding of the immune system and develop potential therapeutics for immune-related diseases.

Product Title:PerCP Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
SKU:AGEL0502
Size:25µg, 100µg
Clone No:M5/114
Synonyms:H2-Ab1/Eb1;Major histocompatibility protein class II beta chain;MHC class II H2-IA-beta-psi;I-E beta MHC class II;MHC class II;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PerCP Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PerCP
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P14483 O78196
Gene ID:14961,14969
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b,d,q,r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.

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