The MTRR Antibody (CAB1462) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in applications such as Western blotting. By targeting the MTRR protein, researchers can analyze its expression and function in various cell types, making it an essential tool for studies in genetics, epigenetics, and cancer research.MTRR, also known as 5-methyltetrahydrofolate-homocysteine methyltransferase reductase, plays a vital role in maintaining proper levels of methyl groups for DNA methylation and synthesis.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
MTRR Antibody
SKU:
CAB1462
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
MSR, cblE, MTRR
Positive Sample:
A-549, HeLa, LO2, 293T
Cellular Localization:
Cytoplasm, Cytoplasm.
Calculated MW:
78kDa
Observed MW:
80kDa
This gene encodes a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. This protein functions in the synthesis of methionine by regenerating methionine synthase to a functional state. Because methionine synthesis requires methyl-group transfer by a folate donor, activity of the encoded enzyme is important for folate metabolism and cellular methylation. Mutations in this gene can cause homocystinuria-megaloblastic anemia, cbl E type. Alternative splicing of this gene results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
4552
RRID
AB_2761493
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MTRR Rabbit pAb (CAB1462) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 20s.
