The MYBPC2 Antibody (CAB13331) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting MyBPC2 in human samples, making it suitable for use in Western blot applications. By targeting the MyBPC2 protein, this antibody allows for the precise identification and analysis of MyBPC2 expression in various cell types, facilitating research in fields such as cardiology, muscular disorders, and exercise physiology.MyBPC2, also known as Myosin Binding Protein C2, plays a crucial role in regulating muscle contraction and maintaining muscle integrity.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
MYBPC2 Antibody
SKU:
CAB13331
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
MYBPC, MYBPCF, fsMyBP-C, MYBPC2
Positive Sample:
Mouse skeletal muscle, Rat skeletal muscle
Cellular Localization:
Cytosol.
Calculated MW:
128kDa
Observed MW:
140kDa
This gene encodes a member of the myosin-binding protein C family. This family includes the fast-, slow- and cardiac-type isoforms, each of which is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The protein encoded by this locus is referred to as the fast-type isoform. Mutations in the related but distinct genes encoding the slow-type and cardiac-type isoforms have been associated with distal arthrogryposis, type 1 and hypertrophic cardiomyopathy, respectively.
Purification Method
Affinity purification
Gene ID
4606
RRID
AB_2760187
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using MYBPC2 Rabbit pAb (CAB13331) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.