The MYLK3 Polyclonal Antibody (CAB6663) is a valuable tool for researchers studying MYLK3, a protein involved in muscle contraction and relaxation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the MYLK3 protein, this antibody allows for the detection and analysis of MYLK3 expression in various cell types.MYLK3, also known as myosin light chain kinase 3, plays a crucial role in regulating smooth muscle contraction and is implicated in various physiological processes such as blood pressure regulation.
Dysfunction of MYLK3 has been linked to cardiovascular diseases and other disorders affecting smooth muscle function. Therefore, studying the expression and activity of MYLK3 is essential for understanding its role in health and disease.Researchers in the fields of cardiovascular biology, muscle physiology, and drug development can benefit from using the MYLK3 Polyclonal Antibody in their studies. By gaining insights into the function of MYLK3, researchers can potentially identify new therapeutic targets for diseases related to smooth muscle dysfunction.
Product Name:
MYLK3 Rabbit Polyclonal Antibody
SKU:
CAB6663
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human MYLK3 (NP_872299.2).
Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).
Purification Method:
Affinity purification
Gene ID:
91807
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Immunofluorescence analysis of U2OS cells using MYLK3 Rabbit pAb (CAB6663). Secondary antibody: Cy3 Goat Anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
