The NCR3 Antibody (CAB7153) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot experiments. By targeting the NCR3 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an excellent choice for investigations in the fields of immunology and oncology.NCR3, also known as Natural Cytotoxicity Triggering Receptor 3, plays a crucial role in the activation and regulation of natural killer cells, key players in the body's defense against infections and tumors.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
NCR3 Antibody
SKU:
CAB7153
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
1C7, MALS, CD337, LY117, NKp30, NCR3
Positive Sample:
Daudi
Cellular Localization:
Cell Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:
22kDa
Observed MW:
22kDa
The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
259197
RRID
AB_2767707
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of lysates from Daudi cells, using NCR3 Rabbit pAb (CAB7153) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
