The NEUROD1 Antibody (CAB1147) is a high-quality antibody developed for reliable detection and analysis of target proteins. This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. RRID AB_2758576 Gene ID 4760 Swiss Prot Synonym T2D; BETA2; BHF-1; MODY6; NEUROD; bHLHa3; NEUROD1
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Rat samples.
Product Name:
NEUROD1 Antibody
SKU:
CAB1147
Size:
100μL, 20μL
Reactivity:
Human, Rat
Clone Number:
-
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:100 - 1:500
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
T2D, BETA2, BHF-1, MODY6, NEUROD, bHLHa3, NEUROD1
Positive Sample:
C6, SH-SY5Y
Cellular Localization:
Cytoplasm, Nucleus.
Calculated MW:
40kDa
Observed MW:
45kDa
This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. RRID AB_2758576 Gene ID 4760 Swiss Prot Synonym T2D; BETA2; BHF-1; MODY6; NEUROD; bHLHa3; NEUROD1
Purification Method:
Affinity purification
Gene ID:
4760
RRID:
AB_2758576
Buffer Information:
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using NEUROD1 Rabbit pAb (CAB1147) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
