The NKX2-8 Monoclonal Antibody (PACO03829) is a valuable tool for researchers studying the NKX2-8 protein, a transcription factor involved in developmental processes and potentially implicated in cancer. This antibody, generated using hybridoma technology, is highly specific for human samples and has been validated for use in immunohistochemistry and Western blot applications.NKX2-8, a member of the NKX family of homeodomain-containing transcription factors, plays a crucial role in embryonic development and has been linked to the regulation of cell differentiation and proliferation.
Its aberrant expression has been observed in various cancer types, suggesting a potential oncogenic role for NKX2-8.By targeting the NKX2-8 protein, researchers can gain insights into its functions in normal and disease states, providing valuable information for cancer biology and developmental studies. The NKX2-8 Monoclonal Antibody is a reliable tool for detecting and analyzing NKX2-8 expression in different cell types and tissues, making it an essential reagent for research in the fields of oncology and developmental biology.
Antibody Name:
NKX2-8 Antibody
Antibody SKU:
PACO03829
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the N-terminal region of human Nkx-2.8.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
Homeobox protein Nkx-2.8
UniProt Protein Function:
NKX2-8: Belongs to the NK-2 homeobox family.Protein type: Transcription factor; Cell development/differentiation; DNA-bindingChromosomal Location of Human Ortholog: 14q13.3Cellular Component: nucleusMolecular Function: sequence-specific DNA binding; double-stranded DNA binding; transcription factor activityBiological Process: transcription from RNA polymerase II promoter; transcription, DNA-dependent; axonogenesis; positive regulation of transcription from RNA polymerase II promoter; liver development; lung development; negative regulation of epithelial cell proliferation
