Description
NOL9 Antibody (PACO15735)
The NOL9 Polyclonal Antibody (PACO15735) is a valuable tool for researchers studying NOL9, a protein involved in various cellular processes including ribosome biogenesis and cell growth. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. It detects the NOL9 protein, allowing for precise and accurate analysis in a variety of cell types.NOL9 is known for its role in ribosome biogenesis, a fundamental process in cells that is essential for protein synthesis. Dysregulation of ribosome biogenesis has been linked to various diseases, making NOL9 an important target for research in cancer, developmental disorders, and other conditions.
By studying the function of NOL9, researchers can gain insights into its impact on cell growth and potential therapeutic strategies targeting this protein.Overall, the NOL9 Polyclonal Antibody is a valuable tool for researchers interested in exploring the role of NOL9 in cellular processes and disease states. Its high reactivity and specificity make it ideal for a wide range of applications in molecular biology and biomedicine.
| Antibody Name: | NOL9 Antibody (PACO15735) |
| Antibody SKU: | PACO15735 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human NOL9 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Hela cells, Primary antibody: PACO15735(NOL9 Antibody) at dilution 1/1250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds. |
| Background: | Nucleolar protein 9 is a protein that in humans is encoded by the NOL9 gene. Polynucleotide 5'-kinase involved in rRNA processing. The kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. In vitro, has both DNA and RNA 5'-kinase activities. Probably binds RNA. |
| Synonyms: | nucleolar protein 9 |
| UniProt Protein Function: | NOL9: Polynucleotide 5'-kinase involved in rRNA processing. The kinase activity is required for the processing of the 32S precursor into 5.8S and 28S rRNAs, more specifically for the generation of the major 5.8S(S) form. In vitro, has both DNA and RNA 5'-kinase activities. Probably binds RNA. Belongs to the Clp1 family. NOL9/GRC3 subfamily. |
| UniProt Protein Details: | Protein type:Nucleolus; EC 2.7.1.- Chromosomal Location of Human Ortholog: 1p36.31 Cellular Component: membrane; nucleolus; nucleoplasm Molecular Function:ATP binding; polynucleotide kinase activity; protein binding Biological Process: cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of 5.8S rRNA; rRNA processing |
| UniProt Code: | Q5SY16 |
| NCBI GenInfo Identifier: | 73921242 |
| NCBI Gene ID: | 79707 |
| NCBI Accession: | Q5SY16.1 |
| UniProt Secondary Accession: | Q5SY16,Q2NL84, Q4VBY3, Q6P472, Q7L4D6, Q96EE0, Q9H5L4 |
| UniProt Related Accession: | Q5SY16 |
| Molecular Weight: | 79,323 Da |
| NCBI Full Name: | Polynucleotide 5'-hydroxyl-kinase NOL9 |
| NCBI Synonym Full Names: | nucleolar protein 9 |
| NCBI Official Symbol: | NOL9Â Â |
| NCBI Official Synonym Symbols: | Grc3; NET6Â Â |
| NCBI Protein Information: | polynucleotide 5'-hydroxyl-kinase NOL9 |
| UniProt Protein Name: | Polynucleotide 5'-hydroxyl-kinase NOL9 |
| UniProt Synonym Protein Names: | Nucleolar protein 9 |
| Protein Family: | Polynucleotide 5'-hydroxyl-kinase |
| UniProt Gene Name: | NOL9Â Â |
| UniProt Entry Name: | NOL9_HUMAN |
