The NAP1 Polyclonal Antibody (PAC019222) is a valuable tool for researchers studying NAP1, a protein involved in various cellular processes. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the NAP1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in molecular biology and cell signaling research.NAP1, also known as nucleosome assembly protein, is essential for the formation of nucleosomes and chromatin remodeling, playing a crucial role in gene expression regulation and DNA replication. Its involvement in these fundamental cellular processes highlights its importance in understanding various biological pathways.
Researchers studying gene regulation, epigenetics, and chromatin organization will find this antibody particularly useful in their investigations.By using the NAP1 Polyclonal Antibody, researchers can gain insights into the function and regulation of this key protein, leading to a deeper understanding of cellular mechanisms and potential implications for diseases such as cancer and developmental disorders. This antibody serves as a valuable tool for advancing research in molecular and cellular biology, offering precise and reliable detection of NAP1 in experimental settings.
Antibody Name:
NPAP1 Antibody (PACO19222)
Antibody SKU:
PACO19222
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:5000, IHC:1:50-1:200
Species Reactivity:
Human
Immunogen:
Synthetic peptide of human NPAP1
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19222(NPAP1 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19222(NPAP1 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene is located in the Prader-Willi syndrome region on chromosome 15. This gene is biallelically expressed in adult testis and brain but is paternally imprinted in fetal brain. Defects in this gene may be associated with Prader-Willi syndrome.
Synonyms:
nuclear pore associated protein 1
UniProt Protein Function:
NPAP1: May be involved in spermatogenesis.Protein type: Unknown functionChromosomal Location of Human Ortholog: 15q11.2Disease: Prader-willi Syndrome
UniProt Protein Details:
NCBI Summary:
This gene is located in the Prader-Willi syndrome region on chromosome 15. This gene is biallelically expressed in adult testis and brain but is paternally imprinted in fetal brain. Defects in this gene may be associated with Prader-Willi syndrome. [provided by RefSeq, Aug 2012]
