The NSUN3 Polyclonal Antibody (CAB12892) is a powerful tool for researchers studying NSUN3, a key enzyme involved in mitochondrial RNA methylation. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the NSUN3 protein, this antibody enables precise detection and analysis of NSUN3 levels in a variety of cell types.NSUN3 is a vital player in mitochondrial RNA metabolism, making it a crucial target for investigation in areas such as mitochondrial dysfunction, metabolic disorders, and cancer.
The functionality of NSUN3 in RNA modification processes highlights its potential as a therapeutic target for diseases characterized by aberrant RNA methylation.The NSUN3 Polyclonal Antibody (CAB12892) provides researchers with a reliable tool for exploring the role of NSUN3 in various biological processes, shedding light on its involvement in disease pathology and potential as a therapeutic target for precision medicine approaches.
Product Name:
NSUN3 Rabbit Polyclonal Antibody
SKU:
CAB12892
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human NSUN3 (NP_071355.1).
Enables tRNA (cytosine-5-)-methyltransferase activity. Involved in regulation of mitochondrial translation and tRNA wobble base cytosine methylation. Located in mitochondrial matrix. Implicated in combined oxidative phosphorylation deficiency 48.
Purification Method:
Affinity purification
Gene ID:
63899
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using NSUN3 Rabbit pAb (CAB12892) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
